DIAMONDS is a study focused on identifying the molecular differences between a broad range of infectious and inflammatory diseases. It is ideally placed to contribute to the international effort to understand how COVID-19 differs from other infections, and how it might be triggering a new syndrome with some features of Kawasaki disease. The case definition of this syndrome, termed Paediatric Inflammatory Multisystem Syndrome – Temporally Associated with SARS-CoV-2 (PIMS-TS) is outlined via the RCPCH guidance (.pdf opens in a new window).
Diamonds will be recruiting patients with possible/confirmed COVID-19 and related illnesses, including PIMS-TS which present to medical care during the Pandemic, with the aim of developing accurate diagnostic and prognostic tests for COVID-19 and understanding the mechanism of PIMS-TS and its relationship to the Pandemic.
Clinicians wanting to enrol patients with COVID-19 or related illnesses (including PIMS-TS) can view an example of the Case Record Form, an introduction to the project (including information about data collection and sample handling), and contact the lead centre in their country (see below).
Links to:
Example Case Record Form (.pdf opens in a new window)
PIMS-TS Case Definition (.pdf opens in a new window)
PIMS-TS Flow (When finalised by ML)
Table of contact point at lead centres in countries (available shortly)
This project has received funding from the European Union’s Horizon 2020 research and innovation programme under grant agreement No. 848196