The University of Zurich (UZH) is one of the leading research universities of Europe. The University Children’s Hospital Zurich – Eleonore Foundation is with ca 200 beds the largest pediatric hospital in Switzerland and one of the leading centers for pediatric and youth medicine in Europa. Innovative basic science research, translational and clinical research are successfully promoted to lead to the generation of new evidence, improved diagnosis and therapy in pediatric health care.
The PINNACLE research group of the pediatric and neonatal intensive care department of the University Children’s Hospital Zurich prospectively recruits pediatric and neonatal patients with febrile and inflammatory conditions. The team also supports and inputs to other activities in work package 1. In addition, together with University of Bern, University Children’s Hospital Zurich has contributed to the Swiss Pediatric Sepsis Study with DNA, RNA, serum, and pathogens of 750 children aged 0-17 years with blood culture-confirmed infection. These samples can serve as a gold standard of confirmed bacterial infections to evaluate and validate promising new genomic, transcriptomic, and phenotypic markers of infection.
The PINNACLE research team of the pediatric and neonatal intensive care department of the University Children’s Hospital Zurich, led by Prof. Luregn Schlapbach (principal investigator for DIAMONDS) and Prof. Cornelia Hagmann is an interdisciplinary group. The team is funded by highly competitive grants and collaborates with several national and international partnerships. Our research focus is broad and diverse, spanning from sepsis and life-threatening infections in critically ill neonates and children, over interventional research, to artificial intelligence.
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This project has received funding from the European Union’s Horizon 2020 research and innovation programme under grant agreement No. 848196